Using homologous recombination to manipulate the genome of human somatic cells.

نویسنده

  • Matthew Porteus
چکیده

Abbreviations: rAAV, recombinant adeno-associated virus; DNA, deoxyribonucleic acid; DSBs, doublestrand breaks; SDSA, synthesis dependent strand annealing; ES, embryonic stem; ESC, embryonic stem cell; HPRT, hypoxanthine phosphoribosyltransferase; HAT, hypoxanthine-aminopterin-thymidine; ITR, inverted terminal repeat; bp, basepair; ZFN, zinc finger nuclease; SCID, severe combined immunodeficiency. Biotechnology and Genetic Engineering Reviews Vol. 24, 195-212 (2007)

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عنوان ژورنال:
  • Biotechnology & genetic engineering reviews

دوره 24  شماره 

صفحات  -

تاریخ انتشار 2007